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10 September 2020

New Research Shows How Coronavirus Infects Different Organs

Article gives proof that early intervention treatment with HCQ, Zpak and Zinc prevent the virus from getting into and damaging the cells

3D medical animation still shot showing the structure of a coronavirus
(photo credit: WWW.SCIENTIFICANIMATIONS.COM)

New research shows how coronavirus infects different organs 

Examining the single-cell RNA expression of 28 genes can help scientists predict which tissues and cell types are most vulnerable to infection. New research shows how coronavirus infects different organs Examining the single-cell RNA expression of 28 genes can help scientists predict which tissues and cell types are most vulnerable to infection.

The study, titled "A Single-Cell RNA Expression Map of Human Coronavirus Entry Factors,” mapped the expression of 28 human genes named "SCARFS" or SARS-CoV-2 and Coronavirus-Associated Receptors and Factors, according to the Cornell Chronicle. Examining the single-cell RNA expression of these 28 genes can help scientists predict which tissues and cell types are most vulnerable to infection.

“You can learn which cells and organs are most likely to be infected – at least at the onset of an infection,” said Cedric Feschotte, professor in the Department of Molecular Biology and Genetics, in the College of Agriculture and Life Sciences. “This is very important to emphasize, because once the virus infects a particular tissue, the [genetic] landscape might shift.”

The coronavirus can turn off an entire branch of the immune system, meaning that naturally occurring restriction factors that are present in tissues serve as the body's main defense against SARS-CoV-2, as the immune system is unable to respond quickly.

Mapping the entry points for the virus is also necessary for trying to predict where the virus will go once it enters the body and may help researchers use those areas as targets for developing drugs against the virus, according to the Cornell Chronicle.

The study found alternate entry paths for the virus into the lungs, central nervous system and heart and supports emerging data that shows that the virus can infect the intestines, kidney and placenta. Specific groups of cell within the prostate and testes may be permissive to the coronavirus and may explain male-specific vulnerabilities.

Since the pandemic began, medical professionals have begun reporting patients with symptoms throughout the body, not just in the respiratory system, including a loss of taste and smell, gastroenterological issues, strokes and epidemiological issues.
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