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04 May 2009

Updated Swine News

Swine Flu Ancestor Born on U.S. Factory Farms
(excerpts)

Scientists have traced the genetic lineage of the new H1N1 swine flu to a strain that emerged in 1998 in U.S. factory farms, where it spread and mutated at an alarming rate. Experts warned then that a pocket of the virus would someday evolve to infect humans, perhaps setting off a global pandemic.

The new findings challenge recent protests by pork industry leaders and U.S., Mexican and United Nations agriculture officials that industrial farms shouldn’t be implicated in the new swine flu, which has killed up to 176 people and on Thursday was declared an imminent pandemic by the World Health Organization.

“Industrial farms are super-incubators for viruses,” said Bob Martin, former executive director of the Pew Commission on Industrial Animal Farm Production, and a long-time critic of the so-called “contained animal feeding operations.”

As Wired.com reported on Tuesday, geneticists studying the composition of viruses taken from swine flu victims described it as the product of a DNA swap between North American and Eurasian swine flu strains.

On Wednesday, Columbia University biomedical informaticist Raul Rabadan added new information on the virus’ family history in a posting to ProMed, a public health mailing list. His description paralleled that of other researchers who had analyzed the new strains, but with an extra bit of detail. Six of the genes in swine flu looked to be descended from “H1N2 and H3N2 swine viruses isolated since 1998.”

Experts contacted by Wired.com agreed with Rabadan’s analysis. For researchers who track the evolution of influenza viruses, the news was chilling.
[....]
H3N2 — the letters denote specific gene variants that code for replication-enhancing enzymes — is the name of a hybrid first identified in North Carolina in 1998, the tail end of a decade which saw the state’s hog production rise from two million to 10 million, even as the number of farms dropped. H3N2 originated in a relatively benign swine flu strain first identified in 1918, but had absorbed new genes from bird and human flus.
[....]
Officials and the pork industry argued this week that a direct link hadn’t been found to pigs, and that the new flu strain had yet to be found in farm animals or workers, both in the United States and at a giant hog factory near the outbreak’s epicenter in La Gloria, Mexico. Owned by a subsidiary of Smithfield Foods, the largest U.S. pork producer and a notorious polluter, the factory processes one million hogs each year.
[....]
On Thursday, Reuters called concern with “evil factory farms in Mexico” one of many “wild theories,” on a par with a conspiracy between Al Qaeda and Mexican drug cartels. Indeed, the location may yet prove coincidental. But absence of evidence at the factory and elsewhere is not evidence of absence.

VISIT WIRED SCIENCE for the remaining long article.

See Also, at bottom page:

Swine Flu Genes From Pigs Only, Not Humans or Birds
Tracking Internet Chatter Helps Spot Swine Flu Outbreak
Google Could Have Caught Swine Flu Early

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